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Comprehensive solutions for every stage of your analytical workflow
How do I select the right HPLC column for my application?
Start with your analyte’s properties — molecular weight, polarity, and charge state. Our Column Selection Guide and application database can help narrow your options. Contact our technical team for personalized recommendations.
What is the typical lifetime of a chromatography column?
Column lifetime depends on sample matrix, mobile phase conditions, and maintenance practices. Typically, 1,000–2,000 injections for well-maintained reversed-phase columns. Our Care & Conditioning manual provides best practices.
Do you offer method development support?
Yes. Our application scientists can assist with method development, optimization, and troubleshooting. We offer both remote consulting and on-site support for complex projects.
How do I handle column back-pressure issues?
Elevated back-pressure typically indicates particulate contamination, buffer salt precipitation, or column void formation. Replace the inlet frit, flush with appropriate solvents, or consult our Troubleshooting Guide.